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Period cramps 101 What causes menstrual cramps and tips for relief Top things to know: Period cramps are most likely caused by high levels of prostaglandins compounds released from the uterine lining before your period You can take the edge off with a heat compress and anti-inflammatory pain medication, like ibuprofen Dietary supplements like calcium, vitamin D, zinc, and magnesium may help reduce cramps, but more research is needed Tracking your cramps with Clue can help you identify patterns and know when to talk to your healthcare provider What are period cramps
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