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B12 injections can interfere with some medications, including chloramphenicol (an antibiotic) and certain cancer treatments

For individuals with a significant B-12 deficiency, B-12 injections are typically administered weekly until levels normalize

However, insulin elevation from food intake activates opposing lipogenic (fat-storing) pathways that can blunt the peptides fat-mobilizing effects

This balanced approach offers optimal energy and weight loss benefits for most users while minimizing side effects [1]

Methods Inclusion Criteria Patients aged 65 years or older visiting the geriatric outpatient clinic or admitted to the geriatric ward at Spaarne Gasthuis, Haarlem and Hoofddorp, Netherlands