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TRPV1 antagonists blocked this effect, confirming receptor involvement

Liraglutide was developed with a view to providing a human GLP-1 analogue with a suitable duration of action for daily use, but, inspired by its beneficial actions, the company now strived to develop a second generation version, optimised not only with respect to duration of action, but also with respect to effects on insulin secretion and food intake

These findings offer novel insights into the mechanisms underlying astaxanthin-induced protection against oxidative stress and inflammatory damage

doi: 10.1016/j.exer.2022.109273