By the mid-1500s CE, tobacco had become the most profitable export from the Spanish and Portuguese colonies of the Americas, primarily Nicotiana tabacum
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Assessment of in vitro COPD models for tobacco regulatory science: Workshop proceedings, conclusions and paths forward for in vitro model use
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There were studies found that in the systemic, CS-induced endothelial dysfunction through the following aspects: firstly, directed toxic effects of CS on endothelial cells