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Examines the mouth: determines the shape, size, and location of the spots

Device Type and Filtration: The type of device, especially whether it is a sub-Ohm model (designed for large vapor clouds), affects nicotine delivery

[4] The writers had tried showing Krusty's real face a few times in early episodes, but decided that it did not look right, although his real face was seen in "Krusty Gets Busted" and "Like Father, Like Clown"

These differences were compared with the net effect of nicotine obtained for each of these parameters by subtracting the mean control value from the mean effect of nicotine (Supplementary Fig

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