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Nicotine and angiogenesis Nicotine acting on 7 nAChRs acutely enhances angiogenesis, promoting endothelial cell migration, proliferation and survival, and enhances the angiogenic response to inflammation, ischemia, and atherosclerosis.(15) On the other hand chronic nicotine treatment in rodents found impairment rather than enhanced angiogenesis mediated by downregulation of vascular nAChRs.(16)

The great German poet Goethe used to say: Smoking makes you blunt

Neuro Toxicology 24: 747753

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2016, FDAs first smoking prevention campaign, The Real Cost, prevented up to 587,000 youth ages 11 to 19 from initiating smoking, half of whom might have gone on to become established adult smokers