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They release a steady, controlled amount of nicotine into the bloodstream throughout the day to help manage withdrawal symptoms by maintaining a steady nicotine level, which can reduce cravings and irritability

This finding is particularly relevant given the growing popularity in young people of e-cigarettes, which deliver as much nicotine as combustible tobacco products. The researchers performed the nicotine studies in both human podocytes and mouse models of diabetic nephropathy

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