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CBD showed strong inhibition of CYP2A6 activity in CYP2A6-overexpressing microsomes using either nicotine or cotinine as substrate, with IC 50,u values of 0.27 0.06 and 0.21 0.14 M for cotinine and 3HC formation, respectively (Table 1)

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also as the participants are dental students, reporting of desirable answers might have occurred

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