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Treatment with nicotine-containing e-cigarette aerosols increased PD-L1 expression ( Figure 1 ) compared with nicotine-free treatment containing only the base elements propylene glycol and vegetable glycerin ( Additionally, in vitro and human studies have shown that e-cigarette aerosols can induce changes of PD-L1 expression in monocytes ( Figure 1 ) compared with controls

The original structure was the equivalent size of 40 football pitches and the surviving structure is two-fifths of the original

Ian Jarrold, the head of research at the British Lung Foundation, said: "These findings represent a significant step forward in helping us achieve a clearer picture about the fascinating and intricate reality of lung health