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Participants will be classified as abstinent if they respond no to both of the following questions: (i) have you smoked any cigarettes (even a puff) in the last 7 days? and (ii) Have you used any tobacco product (i.e., chew, snuff, pipe, cigar, etc.) in the last 7 days? Self-report will be biochemically confirmed with expired CO at each in-person visit and urinary anabasine at week 13

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The alcohol intake on the first day of access increases as a function of the deprivation period, which suggests that the reinforcing properties of alcohol increase when the abstinence period increases (Heyser et al., 1997)

"A person with HIV who consistently takes HIV medicines but smokes is much more likely to die of a smoking-related disease than of HIV itself." "We show that even people who have been smoking till age 60 but quit at age 60 have a substantial increase in their life expectancy compared to those who continue to smoke, so it's never too late to quit," Reddy said