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The chemicals in cigarette smoke damage blood vessels, leading to atherosclerosis (hardening and narrowing of the arteries) and an increased risk of blood clots

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This risk goes up when people take Vyvanse in higher doses than directed or misuse it without a legitimate prescription

They repeated the analyses among subgroups of healthy respondents who had no self-reported chronic conditions, and whose self-rated overall health was good, great, or excellent

Beyond the numbers, the 2025 edition reflects a qualitative shift: an increasing convergence between countries of very different income levels