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They were then subjected to the Purdue Pegboard Dexterity Test, which involves picking up pins and placing them in sequential holes

This process of encroachment by a democratic despot, described in Chapter 6, illuminates De Tocquevilles concern over a centralized political leadership described in Chapter 7: It results from the very constitution of democratic nations and their needs that the power of the sovereign must be more uniform, more centralized, more extended, more penetrating, and more powerful in them than elsewhere (666)

Tissues were processed routinely, embedded in paraffin, sectioned at 4 m (peripheral) or 5 m (brain), and stained with hematoxylin and eosin for analysis by light microscopy