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In 2020, 22.5% of youths used an e-cigarette

Another systematic review which looked at 38 studies (20 studies with control groups, 15 cohort studies, three cross-sectional studies, and two clinical trials) found that the odds of quitting cigarette smoking were 28% lower in those who used e-cigarettes compared with those who did not use e-cigarettes

), it was shown that the presence of flavoring agents might have a role in increased IL-1, IL-6, and TNF- levels and other oxidative stress markers in lungs