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45), with the latter posing greater metabolic burden and safety concerns

When cytoplasmic iron levels decrease, ferritin is able to release iron through ferritin autophagy, a process that is facilitated by nuclear receptor coactivator 4 (NCOA4) [39]

Antioxidant enzymes such as catalase, SOD, and GPx have the potential to protect neurons from oxidative damage and neurodegeneration

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