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However, a type of spontaneous variant that originated from flue-cured varieties has a reddish hue in flue-cured leaves and has historically been referred to as Cherry Red tobacco ( N -demethylase gene CYP82E4 , which plays a key role in nicotine to nornicotine conversion ( o -quinones (produced by oxidation of chlorogenic acid and caffeic acid by polyphenol oxidase) to generate red color (570 nm wavelength) in Cherry Red tobacco ( During several years of field observations, we identified a spontaneous Cherry Red variant (CR60) that originated from flue-cured cultivar Yunyan87 (Y87)

Withdrawal While nicotine withdrawal can be unpleasant, it is temporary

From the 60s and 70s, the tobacco industry marketed low-tar cigarettes as safer versions of their normal cousins

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