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Rats who inhaled secondhand marijuana smoke for just one minute experienced significant constriction in their capillaries, according to a 2016 study published in the Journal of the American Heart Association

Note: there is some light background scuffing and wear as well as some discoloration areas to blue color of non-graphic top, also has some scattered spotting to background and edges of the hinged lid

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add_main_imageITCs shares closed 7.95 higher at 346.25 each on BSE Ltd, while the bourses benchmark Sensex gained 0.95%, to close at 28,930.41 points

Specific findings include the following: Reduction of the mouth opening (trismus) Stiff and small tongue Blanched and leathery floor of the mouth Fibrotic and de-pigmented gingiva Rubbery soft palate with decreased mobility Blanched and atrophic tonsils Shrunken budlike uvula Sinking of the cheeks, not commensurate with age or nutritional status Stage 3 Leukoplakia is precancerous and is found in more than 25% of individuals with oral sub-mucous fibrosis