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Mar Pollut Bull 209:117253

Varenicline also binds with moderate affinity (Ki = 350 nM) to the 5-HT3 receptor

For the uninitiated, vaping is the inhaling of an aerosol mist from an electronic cigarette or other similar device, which heats up a liquid containing nicotine to create a vapor that looks like smoke

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Nicotine can influence the metabolism of certain antidepressants, particularly selective serotonin reuptake inhibitors (SSRIs) and tricyclic antidepressants (TCAs)