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Long-term NRT use is considered safer than continued smoking, though it's best done under medical supervision to avoid NRT dependency

A total of 267,153 participants joined the Study by completing a baseline questionnaire (between January 2006 and December 2009) and giving signed consent for linkage of their information to routine health databases

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Several of these substances are already included on the FDAs HPHC list, while others have recently been added