Early casecontrol studies observed that smokers had approximately twice the risk of developing bladder cancer compared to non-smokers, and a large prospective cohort study in Australia further reported that smoking accounted for nearly 50% of the total bladder cancer burden
Users transitioning from low daily cigarette use should start with lower nicotine strengths, such as 2% (20 mg/ml)
Proctor (December 1996), "The anti-tobacco campaign of the Nazis: a little known aspect of public health in Germany, 193345", British Medical Journal , 313 (7070): 14501453, doi:10.1136/bmj.313.7070.1450, PMC 2352989, PMID 8973234 "Research on Smoking and Lung Cancer: A Landmark in the History of Chronic Disease Epidemiology"
At the same its much safer, because youre not inhaling hot, often toxic gases and particles of burned tobacco
Cigarette beetles commit most of their damage while in their larvae stage