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What distinguishes Marlboro, Camel, and Newport is their proprietary flavor blends: carefully tuned combinations of sugars, cocoa, licorice, menthol, acids, and aroma compounds

Retaining nicotine at pleasurable or addictive levels while reducing the more toxic components of tobacco is another general strategy for harm reduction (for a recent review of this issue, see Russell, in Ferrence et al., 2000)

European Guidelines on cardiovascular disease prevention in clinical practice (version 2012)

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