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These changes lasted several days and may correspond to the anxiety and depression experienced by humans for several days after quitting smoking "cold turkey." The results of this research may help in the development of better treatments for the nicotine withdrawal symptoms that may interfere with individuals' attempts to quit

Valadeau et al., 2010

For in vivo experiments, both male and female mice were exposed to one puff of nicotine or cannabidiol aerosols for five days a week

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Choose low THC products (less than 10% or 2.5mg THC for edibles), use once per week or less, and do not drive after consuming