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In order to decrease the adverse effects of nicotine after entering the gastrointestinal tract and obtain a localized delivery in the oral cavity, nicotine may be incorporated into a nanocarrier system

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Fire-cured tobacco typically takes between 10-13 weeks and is used to make pipe tobacco and chewing tobacco

Stead LF, Carroll AJ, Lancaster T

2 Sometimes, the tobacco in a hookah is combined with honey, sugarcane, dried fruits, spices or flavors, giving it a sweet smell