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doi: 10.1016/j.ntt.2012.09.003.93 [93] Liu J, Leung PW, McCauley L, Ai Y, Pinto-Martin J

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A valid-PRS established based on such a process thus fulfils the definition of an instrumental variable mentioned above if it remains associated with the designated phenotype of interest

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Medications can interact with nicotine and alter the buzz by affecting how nicotine is metabolized