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Other types of cancer : Tobacco use causes at least 15 different types of cancer, including cancer of the larynx, esophagus, mouth, throat, kidney, bladder, liver, pancreas, stomach, cervix, colon and rectum, and acute myeloid leukemia, according to an article titled, How does smoking cause cancer? from Cancer Research UK

The effect occurs when nicotine is absorbed into the bloodstream through the oral mucosa

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Its like the heart disease story

If youre a heavier smoker, you may prefer 610mg, but its usually best not to jump straight to very high strengths as you need to get used to absorbing nicotine through your mouth first