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In vitro ALI culture (time course) For the in vitro time course ( n = 20 timepoints), we used tracheal cells from three donors that included a heavy smoker, light smoker, and non-smoker used above for in vivo scRNA-seq

Smoking for a long time can cause emphysema, a type of chronic obstructive lung disease (COPD)

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A blockage inside the intestines prevents the body from expelling waste

The FDA says menthol interacts with nicotine in the brain to enhance nicotines addictive effects, and the combination of menthols flavor, sensory effects and interaction with nicotine in the brain increases the likelihood that young people who start using menthol cigarettes will progress to regular use