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10.1016/j.ajpath.2014.03.005[Epub ahead of print]

A well-designed study (double-blind, placebo) looked at CBD's effect on anxiety with the following results: Anxiety scores decreased within the first month in 57 patients (79.2%) and remained decreased during the study duration

Theres disagreement regarding the ideal cutoff used in the nomogram: The original nomogram line separating possible toxicity from unlikely toxicity was based on a 4-hour acetaminophen concentration of 200 mcg/mL