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Public Health England found in their studies that "At normal settings, there was no or negligible formaldehyde release. However, there are concerns about how this will affect those who vape at very high temperatures, as hotter devices might put users at risk of inhaling higher levels of formaldehyde

However, lung cancer incidence and mortality rates differ substantially across the world, reflecting varying patterns of tobacco smoking, exposure to environmental risk factors and genetics

To overcome this limitation, both Karey et al

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But theres another, often-forgotten factor that helped cigarettes conquer the world: technology