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More than 2,000 reports of severe lung disease after e-cigarette use, and 39 deaths after vaping, have been reported There is concern about the long-term effect of other compounds found in e-cigarettes, especially in regards to cancer since a number of these compounds are known potential carcinogens, said Faisal Khan, MD, Medical Director, Interventional Pulmonology and Endoscopy at Franciscan Health Indianapolis