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In a 12-month clinical trial involving 404 HIV-infected patients with excess abdominal fat, Tesamorelin (2 mg daily) significantly reduced visceral adipose tissue (VAT) compared to placebo

For individuals who want to maintain normal eating patterns, avoid central appetite manipulation, cannot tolerate GLP-1 side effects, or prefer targeted fat metabolism enhancement without hunger modification, AOD-9604 offers an alternative mechanism

The researchers concluded that AOD-9604 represents a promising fat-reducing alternative to growth hormone therapy without its associated metabolic risks, particularly regarding glucose regulation and IGF-1 elevation

Unlike systemic fat burners, which often lead to overstimulation of the nervous system, AOD-9604 acts at the cellular level, sending a signal directly to adipocytes (fat cells) ordering them to release stored fatty acids

Evidence comes from preclinical animal models and community protocols