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10.1016/j.scitotenv.2020.141049 223 WangF.LiuY.NiF.JinJ.WuY.HuangY.et al (2022b)

Research suggests that cagrilintides body-weight-related effects depend on brain amylin receptor pathways, especially AMY1R and AMY3R

While reducing USP7 activity via RNA interference or pharmacological inhibition lengthened circadian period in MEFs and U2OS cells (Papp et al., 2015), other studies reported the opposite effect, with knockdown shortening and overexpression lengthening the period (Maier et al., 2009