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Globally, around 40% of the youngsters, 35 percent of women, as well as 33% of males are frequently uncovered by indoor smoke in the vicinity [3]

Nicotine C-oxidation to nicotine 5(1)iminium ion is followed by a second oxidation that generates cotinine, which is further metabolized to trans 3-hydroxycotinine (3-HCOT), a reaction that is catalyzed almost exclusively by CYP2A6 (see Fig

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A prospective study of obesity and risk of coronary heart disease in women