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10.1073/pnas.0913572107 22 JonesH.Rowland-YeoK

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841 A key aspect of these structures was that the apo- and holo (cofactor-bound)-IcmF dimers were found to adopt open and closed states, which are representative of a structure ready to accept cofactor from ATR and the catalytically competent and cofactored state, respectively, a finding that parallels subsequent work in human MMUT-MMAA complex