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Exclusion criteria included the following: elevated depressive symptoms, defined as a score of 16 or higher on the Center for Epidemiologic Studies Depression Scale (CES-D) [15], use of medications affecting mood or ovarian hormones (e.g., anti-depressants, anxiolytics, hormonal birth control), current use of smoking cessation aids or programs, self-reported psychiatric disorders (e.g., bipolar disorder, psychotic disorder), and pregnancy and lactation (either currently or in the last 12 months)

They used to think that that was what these things do, that they treated a chemical imbalance

ZYBAN is contraindicated in patients with a known hypersensitivity to bupropion or other ingredients of ZYBAN

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