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While South American populations have used coca leaves for centuries in social and religious settings to ward off hunger and fatigue, cocaine in the US is generally sold as a fine, white, crystalline powder

And one of the unique features of most of the Blue Zones is that particularly the men are heavy smokers

Collectively, our findings emphasize brain regions (e.g., vmPFC, insula, thalamus) and circuits (e.g., insula-thalamus) linked with chronic smoking, suggest neuroimaging paradigms warranting additional consideration among smokers (e.g., pain processing), and point to regions in need of further elucidation in addiction (e.g., cerebellum)

In short, great stuff!"..." more

A person who smokes multiple joints a day may be considered a heavy user even if they only smoke once a week