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As the outgrowth number increased, the expression of P/S cell markers (CK5, CK14 and p63) in the BEC cultures and explants significantly decreased in both smokers and COPD patients, and this was most prominent in patients with COPD

35 Fazekas score had the second strongest attenuating influence on results, suggesting that subclinical vascular disease secondary to cigarette smoking might also have a role in the association between smoking and cortical changes

Experts advise healthy adults need between seven and nine hours of sleep every night