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Definition Crohns disease is a chronic, relapsing-remitting inflammatory bowel disease (IBD) characterized by transmural (full-thickness) inflammation that can affect any segment of the gastrointestinal tract from the mouth to the anus
Gastrointestinal Adverse Reactions In the pool of placebo-controlled trials in adults, gastrointestinal adverse reactions occurred more frequently among patients receiving MOUNJARO than placebo (placebo 20.4%, MOUNJARO 5 mg 37.1%, MOUNJARO 10 mg 39.6%, MOUNJARO 15 mg 43.6%)
The maximum recommended dose varies based on the specific indication and individual patient factors, but generally does not exceed 2.5 mg weekly for most patients
There is no evidence from long-term use in patients with pernicious anemia that cyanocobalamin is carcinogenic