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Source: Huberman Lab podcast, "Peptides: The Science, Uses & Safety" with Dr

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When present, usually mild and transient

Homer1a drives homeostatic scaling-down of excitatory synapses during sleep

It also means cagrilintide could potentially be an option for people who dont respond well to GLP-1-based medications, or who experience side effects that make GLP-1 drugs hard to tolerate