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HILIC stands for hydrophilic interaction liquid chromatography

Any effect it has comes through nicotine's influence on appetite and metabolism and those effects are modest, inconsistent, and tend to fade over time

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While this may seem to give a good indication of sales developments, the study only included one state that borders Massachusetts: Connecticut, where there was no real change in sales, chiefly because that states tobacco taxes are extremely high

Wilding JP, Gilbey SG, Bailey CJ, Batt RA, Williams G, Ghatei MA et al (1993)