While recall bias could potentially affect the validity of some of the included predictors (e.g., frequency of cannabis use), we had restricted the correlation analyses to variables relating to past year behaviors (e.g., frequency of cannabis use in the last year) only, to minimize the risk of bias
These major factors include increased craving in SZ, modulating negative symptoms, pro-cognitive effects of nicotine, and genetic factors ( It has been proposed that due to the pathophysiology of SZ, these individuals may have an enhanced experience of the reinforcing effects of nicotine ( There appears to be a link between the enhanced reinforcing effects of nicotine and the role that negative affect has on increasing the smoking rate in SZ
Some arsenic compounds have been linked to cancer of the lung, skin, liver and bladder
Wootton, R
Activity in the brain's dopamine system might be one explanation of a possible causal link between smoking and psychosis, says study co-author Professor Robin Murray also of King's College London's Institute of Psychiatry