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Other dangers associated with e-cigarettes Between 2009 and 2016, there were 195 e-cigarette explosion-related injuries and fires, resulting in 38 severe injuries

In addition, stimulation of the VTA by nicotine has a regulating effect on serotonin release in the dorsal raphe mediated by inhibitory GABergic interneurons ( Figure 1 These potential benefits of smoking, however, are contrasted by more severe detrimental effects

Around 1 in 3 adults in the UK (around 16 million) is affected, with many remaining undiagnosed for years until serious cardiovascular complications arise, such as a heart attack or stroke

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