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Paul was born in 2007 with several major congenital heart defects, and has had three open-heart surgeries, eight angioplasties and a stomach surgery unrelated to his heart condition

Meanwhile, PMFTC Inc., the local affiliate of PMI in the Philippines, said it continues to evaluate market and regulatory conditions for the introduction of IQOS

I'm looking for something more concrete indicating what caused it to be used in this context

And then Victor gets them

In a recent meta-analysis published in Nature by Jung et al., the researchers utilized a novel approach of investigating population-level smoking metrics as a moderator between maternal smoking and ASD in offspring [119]