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"The research papers on plain packages shows that 81% of smokers think about quitting at least once a day, and 70% find cigarettes less satisfying, while 66% think that the cigarettes have suffered a drop in quality," Pakdemirli said, as he called on smokers to take a step toward quitting

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Additionally, if the LED indicator (if present) blinks or remains off during use, its a sign the battery has drained

This effect occurs because nicotine stimulates both the central and enteric nervous systems, which regulate the functions of the gastrointestinal (GI) tract