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132 Another controlled trial that included 120 subjects with tinnitus and low cochlear blood flow related to Mnire disease found 150 mg of Pycnogenol per day for six months improved cochlear blood flow and reduced subjective measures of tinnitus compared with no treatment

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The diagnosis of adult-onset Stills disease (AOSD) was based on the Yamaguchi criteria, after exclusion of infectious, hematologic, and autoimmune diseases

These studies investigate antioxidant-related mechanisms and their contribution to tissue protection in experimental gastrointestinal and systemic inflammation models