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While developed countries were faster to embrace non-smoking policies than developing and underdeveloped countries, over time, it was clear that efforts to curb smoking were making an impact globally[xiv]

It also said there was no valid evidence filters were reducing the danger

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Nicotine, cotinine and 3-hydroxy-cotinine (OH-cotinine) were measured in PBS using a quantitative liquid chromatography coupled to tandem mass spectrometry (LCMS/MS) method, based on a previously validated method for saliva (as established in 39 )

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