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Thirdly, although most of the participants of the gut microbial GWAS were ancestrally Europeans, the ethnic proportion was not perfectly matched between the two samples (i.e., the exposure GWAS and the outcome GWAS dataset), which may result in some levels of inconsistency in LD correlations

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ETHICAL APPROVAL AND INFORMED CONSENT Ethical approval was obtained from the Human Experimentation Committee Research Institute for Health Sciences (RIHES), Chiang Mai University, Chiang Mai, Thailand (Approval number: 31/2021