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In addition, the functional characterization of EVs from long-term smokers and E-cigarette users with and without BC will be central to clarifying the public health implications of these results

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Chronic bronchitis (J41.x, J42): Defined clinically as productive cough for at least 3 months per year for 2 consecutive years, as established by the WHO criteria

A study in a convenience sample of US smokers found that approximately one-third would prefer to purchase their cigarettes in a 10-pack rather than a 20-pack, with most (70%) believing that the smaller pack would help limit their smoking, and two-thirds indicating that they would be willing to pay at least a 10% price premium to buy the 10-pack [21]