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There is evidence that lung-tissue damage is possible with prolonged use

Summary Keywords tobacco smoking, bioinformatics, cancer, single-nucleotide polymorphisms, DNA methylation, carcinogenic chemicals, health risk Citation Al-Obaide MAI, Ibrahim BA, Al-Humaish S and Abdel-Salam A-SG (2018) Genomic and Bioinformatics Approaches for Analysis of Genes Associated With Cancer Risks Following Exposure to Tobacco Smoking

While in other blends it serves to complement and highlight some of the other components, here it offers a new perspective of sorts framing the other varietals in a robust, almost cigar-like body and flavor, with the Latakia and Turkish offering a peppery smokiness you normally wouldn't find in Virginia/Periques, for example

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And some stores only sell flavored tobacco products