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Fukushima J Med Sci (2015) 61(2):12530.10.5387/fms.2015-14 62 Prez-RubioGLpez-FloresLARamrez-VenegasANo-DazVGarca-GmezLAmbrocio-OrtizEet alGenetic polymorphisms in CYP2A6 are associated with a risk of cigarette smoking and predispose to smoking at younger ages