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These are the first combusted cigarettes to be designated as MRTPs and the second tobacco products overall to receive exposure modification orders, which allows them to be marketed as have a reduced level of a substance

10.1016/j.ausmj.2011.05.003

Differences in risks of developing lung cancer due to PM2.5 geolocation There are significant geographic differences in lung cancer incidence and mortality caused by PM2.5 exposure globally (Table 1)