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There have been some reports of pulmonary aspiration (a complication where food from your stomach is inhaled into your lungs) while under general anesthesia or deep sedation in people taking tirzepatide, likely due to delayed stomach emptying

While it depends on the person and the dose, clinical trials showed that four weeks after starting retatrutide, some people had already lost almost 5% of their body weight

TB-500 distributes systemically, so injection site precision matters less

This then become a chronic issue with associated pain